Article
Recombinant mistletoe lectin induces p53-independent apoptosis in tumour cells and cooperates with ionising radiation.
British journal of cancer - 2 Jun 2003
Hostanska K, Vuong V, Rocha S, Soengas M S, Glanzmann C, Saller R, Bodis S, Pruschy M
Abstract excerpt
Mistletoe extracts are used as alternative cancer treatment in addition to standard chemotherapy and radiation treatment and have an immunostimulatory and pain-relieving effect. A direct antitumour effect of mistletoe extracts against tumour cells of lymphoid origin has been linked to the D-galactoside-specific mistletoe lectin I. In this study, we investigated the cellular effect of bacterially expressed,...
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