Article
The major envelope protein, GP5, of a European porcine reproductive and respiratory syndrome virus contains a neutralization epitope in its N-terminal ectodomain.
The Journal of general virology - 1 Jun 2003
Wissink E H J, van Wijk H A R, Kroese M V, Weiland E, Meulenberg J J M, Rottier P J M, van Rijn P A
Abstract excerpt
A set of neutralizing monoclonal antibodies (mAbs) directed against the GP(5) protein of European type porcine reproductive and respiratory syndrome virus (PRRSV) has been produced previously (Weiland et al., 1999). This set reacted with a plaque-purified virus (PPV) subpopulation of Dutch isolate Intervet-10 (I-10), but not with the European prototype PRRSV LV. In order to map the neutralization epitope in the...
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