Article
Mutations arise independently of transcription in non-dividing bacteria.
Molecular genetics and genomics : MGG - 1 Jul 2003
Barionovi D, Ghelardini P, Di Lallo G, Paolozzi L
Abstract excerpt
It has been proposed that transcription introduces a bias into the random process of mutation. Although this hypothesis is supported by experimental data for mutations arising during active bacterial growth, the role of transcription in mutagenesis in non-dividing bacteria is entirely hypothetical. In the present study, we tested the hypothesis of a possible role of transcription in a non-dividing E. coli K12...
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