Article
Tomato yellow leaf curl Sardinia virus rep-derived resistance to homologous and heterologous geminiviruses occurs by different mechanisms and is overcome if virus-mediated transgene silencing is activated.
Journal of virology - 1 Jun 2003
Lucioli Alessandra, Noris Emanuela, Brunetti Angela, Tavazza Raffaela, Ruzza Valentino, Castillo Araceli G, Bejarano Eduardo R, Accotto Gian Paolo, Tavazza Mario
Abstract excerpt
The replication-associated protein (Rep) of geminiviruses is involved in several biological processes brought about by the presence of distinct functional domains. Recently, we have exploited the multifunctional character of the Tomato yellow leaf curl Sardinia virus (TYLCSV) Rep to develop a molecular interference strategy to impair TYLCSV infection. We showed that transgenic expression of its N-terminal 210...
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