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Article

MHC class I up‐regulation by flaviviruses: Immune interaction with unknown advantage to host or pathogen

20 May 2003

Abstract excerpt

In contrast to many other viruses that escape from cytotoxic T cell recognition by down-regulating major histocompatibility complex class I-restricted antigen presentation, flavivirus infection of mammalian cells up-regulates cell surface expression of major histocompatibility complex class I molecules. Two putative mechanisms for flavivirus-induced major histocompatibility complex class I up-regulation, one via...

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Identifiers

PMID: 12752686
DOI: 10.1046/j.1440-1711.2003.01161.x

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