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Article

Susceptibility loci for complex regional pain syndrome.

Pain - 1 May 2003

van de Beek Willem-Johan T, Roep Bart O, van der Slik Arno R, Giphart Marius J, van Hilten Bob J

Abstract excerpt

An association between HLA-DR13 and patients with complex regional pain syndrome (CRPS) who progressed towards multifocal or generalized tonic dystonia was recently reported. We now report on a new locus, centromeric in HLA-class I, which was significantly associated with a spontaneous development of CRPS, suggesting an interaction between trauma severity and genetic factors conferring CRPS susceptibility....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12749963
DOI: 10.1016/s0304-3959(02)00444-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Susceptibility loci for complex regional pain syndrome.PMID 12749963Read ↗

Multifocal or generalized tonic dystonia of complex regional pain syndrome: a distinct clinical entity associated with HLA-DR13.Semantic proximity Read ↗

Genetic HLA associations in complex regional pain syndrome with and without dystonia.Semantic proximity Read ↗

DNA methylation profiles are associated with complex regional pain syndrome after traumatic injurySemantic proximity Read ↗

Genome-Wide Expression Profiling of Complex Regional Pain SyndromeSemantic proximity Read ↗

HLA-B62 and HLA-DQ8 are associated with Complex Regional Pain Syndrome with fixed dystonia.Semantic proximity Read ↗

Increased risk of persistent neuropathic pain after traumatic nerve injury and surgery for carriers of a human leukocyte antigen haplotype.Semantic proximity Read ↗

A polymorphic locus in the intron 16 of the human angiotensin-converting enzyme (ACE) gene is not correlated with complex regional pain syndrome I (CRPS I).Semantic proximity Read ↗

Increased Risk of Complex Regional Pain Syndrome in Siblings of Patients?Semantic proximity Read ↗

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