Article
Saccharomyces cerevisiae PIP2 mediating oleic acid induction and peroxisome proliferation is regulated by Adr1p and Pip2p-Oaf1p.
The Journal of biological chemistry - 25 Jul 2003
Rottensteiner Hanspeter, Wabnegger Leila, Erdmann Ralf, Hamilton Barbara, Ruis Helmut, Hartig Andreas, Gurvitz Aner
Abstract excerpt
Saccharomyces cerevisiae genes involved in fatty acid degradation contain in their promoters oleate response elements (OREs) and type 1 upstream activation sequences (UAS1s) that bind Pip2p-Oaf1p and Adr1p, respectively. The promoter of the PIP2 gene was found to contain a potential UAS1 that consists of a tandem array of CYCCRR half-sites in an overlapping arrangement with a previously characterized ORE....
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