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Article

The molecular phenotype of polycystic ovary syndrome (PCOS) theca cells and new candidate PCOS genes defined by microarray analysis.

The Journal of biological chemistry - 18 Jul 2003

Wood Jennifer R, Nelson Velen L, Ho Clement, Jansen Erik, Wang Clare Y, Urbanek Margrit, McAllister Jan M, Mosselman Sietse, Strauss Jerome F

Abstract excerpt

Polycystic ovary syndrome (PCOS) affects 5% of reproductive aged women and is the leading cause of anovulatory infertility. A hallmark of PCOS is excessive theca cell androgen secretion, which is directly linked to the symptoms of PCOS. Our previous studies demonstrated that theca cells from PCOS ovaries maintained in long term culture persistently secrete significantly greater amounts of androgens than normal...

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PMID: 12734205
DOI: 10.1074/jbc.M300688200

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GATA6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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