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Article

Genotoxic stress response gene expression in the mid-organogenesis rat conceptus.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Jul 2003

Vinson Robert K, Hales Barbara F

Abstract excerpt

The ability of the conceptus to respond to genotoxic stress may be critical for normal development, particularly after exposure to genotoxic teratogens. Members of the phosphatidylinositol 3-kinase (PI3K) superfamily are involved in controlling cell cycle activity and maintaining genomic stability. The expression of PI3K family members ATM, ATR, and DNA-PKcs, and downstream genes p53, GADD45, and p21, was...

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Share to Cyclophosphamide
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oligonucleotide Array Sequence Analysis

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Share to Phosphatidylinositol 3-Kinases

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Source

Identifiers

PMID: 12730623
DOI: 10.1093/toxsci/kfg097

Genes

ATM
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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