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Article

Functional analysis of AtHKT1 in Arabidopsis shows that Na(+) recirculation by the phloem is crucial for salt tolerance.

The EMBO journal - 1 May 2003

Berthomieu Pierre, Conéjéro Geneviève, Nublat Aurélie, Brackenbury William J, Lambert Cécile, Savio Cristina, Uozumi Nobuyuki, Oiki Shigetoshi, Yamada Katsuyuki, Cellier Françoise, Gosti Françoise, Simonneau Thierry, Essah Pauline A, Tester Mark, Véry Anne-Aliénor, Sentenac Hervé, Casse Francine

Abstract excerpt

Two allelic recessive mutations of Arabidopsis, sas2-1 and sas2-2, were identified as inducing sodium overaccumulation in shoots. The sas2 locus was found (by positional cloning) to correspond to the AtHKT1 gene. Expression in Xenopus oocytes revealed that the sas2-1 mutation did not affect the ionic selectivity of the transporter but strongly reduced the macro scopic (whole oocyte current) transport activity. In...

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Identifiers

PMID: 12727868
DOI: 10.1093/emboj/cdg207
PMCID: PMC156079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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