Article
Phenotypic plasticity of human articular chondrocytes.
The Journal of bone and joint surgery. American volume - 1 Jan 2003
Tallheden T, Dennis J E, Lennon D P, Sjögren-Jansson E, Caplan A I, Lindahl A
Abstract excerpt
BACKGROUND: Progenitor cells in mesenchymal tissues are important in the maintenance of tissue homeostasis and regeneration capacity. Articular cartilage is a tissue with a very low capacity for repair. One explanation could be the lack of chondrogenic progenitor cells within the adult tissue. As a test of chondrogenic differentiation potential, we examined the ability of isolated chondrocytes to take on several...
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