Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis.

doi:10.1902/jop.2003.74.3.329

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Article

Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis.

Journal of periodontology - 1 Mar 2003

Sahingur Sinem E, Sharma Ashu, Genco Robert J, De Nardin Ernesto

Abstract excerpt

BACKGROUND: Fibrinogen is one of the acute-phase proteins whose levels are elevated during periodontal disease. Recent studies suggest that excessive fibrinogen production might play a role in upregulating host immune responses. In addition, there is a relationship between the -455G/A polymorphism (HaeIII) in the 5' flanking region of the beta-fibrinogen gene promoter and increased fibrinogen levels. In this...

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Identifiers

PMID: 12710752
DOI: 10.1902/jop.2003.74.3.329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.