Article
HLA-DRB genotyping in Gilles de la Tourette patients and their parents.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 May 2003
Schoenian Sarah, Konig Inke, Oertel Wolfgang, Remschmidt Helmut, Ziegler Andreas, Hebebrand Johannes, Bandmann Oliver
Abstract excerpt
Gilles de la Tourette syndrome (GTS) is a common neuropsychiatric disorder of unknown cause. There is, however, growing evidence that both autoimmune and genetic factors are involved in the pathogenesis of GTS. In classical autoimmune disorders such as diabetes mellitus or multiple sclerosis, genetic susceptibility is at least in part conferred by human leucocyte antigen (HLA-) subtypes, in particular by distinct...
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