Article
The temperature stability of mouse retroviruses depends on the cholesterol levels of viral lipid shell and cellular plasma membrane.
Virology - 30 Mar 2003
Beer Christiane, Meyer Anika, Müller Katja, Wirth Manfred
Abstract excerpt
To delineate parameters contributing to the extracellular lifetime of retroviral vectors, we carried out stability tests of retroviruses derived from cell lines of different origin and kept under different cultivation conditions. Results show that amphotropic mouse retroviruses (MLV-A) derived from human and hamster cells exhibit 2- to 3-fold higher half-lives compared to retroviruses from mouse cells....
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