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Article

Progressive dystonia in a 12-year-old boy.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society - 1 Jan 2003

Klepper Jörg, Schaper Jörg, Raca Gordana, Coryell Jason, Das Soma, Hayflick Susan J, Voit Thomas

Abstract excerpt

Pantothenate kinase-associated neurodegeneration (PKAN) (MIM 234200; Hallervorden-Spatz syndrome) is a degenerative, autosomal recessive disorder in childhood, currently without specific treatment. In contrast to variable clinical features, T2-weighted magnetic resonance images show a characteristic 'eye-of-the-tiger sign' in the globus pallidus due to excess iron deposition. Recently a defect in pantothenate...

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Source

Identifiers

PMID: 12697433
DOI: 10.1016/s1090-3798(03)00019-9

Genes

PANK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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