Article
Flecainide test in Brugada syndrome: a reproducible but risky tool.
Pacing and clinical electrophysiology : PACE - 1 Jan 2003
Gasparini Maurizio, Priori Silvia G, Mantica Massimo, Napolitano Carlo, Galimberti Paola, Ceriotti Carlo, Simonini Stefano
Abstract excerpt
The flecainide test is widely used in Brugada syndrome. However, its reproducibility and safety remain ill-defined. This study included 22 patients (18 men, mean age 34 years). Mutations in the SCN5A gene were found in eight patients. Two patients had aborted sudden cardiac death, 8 had syncope/presyncope, and 12 were asymptomatic. The ECG was diagnostic in 19 patients and suggestive in 3. At baseline, 21 of 22...
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