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Article

Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome.

Journal of cardiovascular electrophysiology - 1 Aug 2006

Meregalli Paola G, Ruijter Jan M, Hofman Nynke, Bezzina Connie R, Wilde Arthur A M, Tan Hanno L

Abstract excerpt

INTRODUCTION: Provocation tests with sodium channel blockers are often required to unmask ECG abnormalities in Brugada syndrome (BrS). However, their diagnostic value is only partially established, while life-threatening ventricular arrhythmias during these tests were reported. We aimed to establish sensitivity, specificity, and safety of flecainide testing, and to predict a positive test outcome from the...

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Identifiers

PMID: 16764707
DOI: 10.1111/j.1540-8167.2006.00531.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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