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Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex.

Molecular genetics and genomics : MGG - 1 Jun 2003

Lu Y-M, Lin Y-R, Tsai A, Hsao Y-S, Li C-C, Cheng M Y

Abstract excerpt

The yeast pet18 mutant exhibits three distinct phenotypes: temperature-sensitive lethality, failure to maintain a dsRNA virus, and respiration deficiency. We have isolated a yeast mutant, H53, with phenotypes identical to those of pet18. Based on PCR and Southern hybridization analysis, H53 was found to result from a large chromosomal deletion extending from YCR019w to YCR028c on chromosome III. Genetic analysis...

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PMID: 12684875
DOI: 10.1007/s00438-003-0835-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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