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Profiling of Temperature-Induced Changes in<i>Borrelia burgdorferi</i>Gene Expression by Using Whole Genome Arrays

24 Mar 2003

Abstract excerpt

Borrelia burgdorferi is the etiologic agent of Lyme disease, the most prevalent arthropod-borne disease in the United States. The genome of the type strain, B31, consists of a 910,725-bp linear chromosome and 21 linear and circular plasmids comprising 610,694 bp. During its life cycle, the spirochete exists in distinctly different environments, cycling between a tick vector and a mammalian host. Temperature is...

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PMID: 12654782
DOI: 10.1128/iai.71.4.1689-1705.2003

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