Article
Large-scale search of SNPs for type 2 DM susceptibility genes in a Japanese population.
Biochemical and biophysical research communications - 21 Mar 2003
Daimon Makoto, Ji Guijin, Saitoh Tamotsu, Oizumi Toshihide, Tominaga Makoto, Nakamura Takahiro, Ishii Keisuke, Matsuura Tadashi, Inageda Kiyoshi, Matsumine Hiroto, Kido Takashi, Htay Lwin, Kamatani Naoyuki, Muramatsu Masaaki, Kato Takeo
Abstract excerpt
The etiology of type 2 diabetes (DM) is polygenic. We investigated here genes and polymorphisms that associate with DM in the Japanese population. Single-nucleotide polymorphisms (SNPs) of 398 derived from 120 candidate genes were examined for association with DM in a population-based case-control study. The study group consisted of 148 cases and 227 controls recruited from Funagata, Japan. No evident...
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