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Article

Homocysteine, folate, vitamin B12 levels, and C677T MTHFR mutation in children with renal failure.

Pediatric nephrology (Berlin, Germany) - 1 Mar 2003

Canepa Alberto, Carrea Alba, Caridi Gianluca, Dertenois Laura, Minniti Giuseppe, Cerone Roberto, Canini Silvana, Calevo Maria Grazia, Perfumo Francesco

Abstract excerpt

Hyperhomocysteinemia is well documented in chronic renal failure (CRF) and premature and progressive occlusive vascular disease is common in CRF. The combined effects of renal failure, folate and vitamin B(12) levels, and a common mutation (C677T) in the methylenetetrahydrofolate reductase (MTHFR) gene that leads to total plasma homocysteine (tHcy) elevation in CRF children were investigated. Forty-two children...

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Source

Identifiers

PMID: 12644913
DOI: 10.1007/s00467-002-1058-0

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Homocysteine, folate, vitamin B12 levels, and C677T MTHFR mutation in children with renal failure.PMID 12644913Read ↗

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