Mutations which uncouple transport and phosphorylation in the D-mannitol phosphotransferase system of Escherichia coli K-12 and Klebsiella pneumoniae 1033-5P14.

doi:10.1128/JB.185.7.2267-2276.2003

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Article

Mutations which uncouple transport and phosphorylation in the D-mannitol phosphotransferase system of Escherichia coli K-12 and Klebsiella pneumoniae 1033-5P14.

Journal of bacteriology - 1 Apr 2003

Otte Susanne, Scholle Annette, Turgut Sevket, Lengeler Joseph W

Abstract excerpt

Mutants of Escherichia coli K-12 were isolated which lack the normal phosphotransferase system-dependent catabolic pathway for D-mannitol (Mtl). In some mutants the pts genes for the general proteins enzyme I and histidine protein of the phosphoenolpyruvate-dependent carbohydrate phosphotransferase systems were deleted. Other mutants expressed truncated mannitol-specific enzymes II (II(Mtl)) which lacked the...

Topics

Amino Acid Sequence
Biological Transport
Cell Division
Conserved Sequence
Escherichia coli
Escherichia coli Proteins
Genetic Engineering
Klebsiella pneumoniae
Mannitol
Monosaccharide Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Site-Directed

Mutation

Phosphoenolpyruvate Sugar Phosphotransferase System

Phosphorylation

Plasmids

Protein Structure, Tertiary

Sequence Deletion

Substrate Specificity

Source

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Identifiers

PMID: 12644498
DOI: 10.1128/JB.185.7.2267-2276.2003
PMCID: PMC151505

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