Article
Inverting the hourglass: quantitative evidence against the phylotypic stage in vertebrate development.
Proceedings. Biological sciences - 22 Feb 2003
Bininda-Emonds Olaf R P, Jeffery Jonathan E, Richardson Michael K
Abstract excerpt
The concept of a phylotypic stage, when all vertebrate embryos show low phenotypic diversity, is an important cornerstone underlying modern developmental biology. Many theories involving patterns of development, developmental modules, mechanisms of development including developmental integration, and the action of natural selection on embryological stages have been proposed with reference to the phylotypic stage....
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