Article
Determination of alpha-1 antitrypsin genetic deficiency in duodenal ulcer by polymerase chain reaction.
JPMA. The Journal of the Pakistan Medical Association - 1 Dec 2002
Shahid A, Siddiqui A A, Sultana T, Qureshi H, Waqar M A, Zuberi S J
Abstract excerpt
OBJECTIVE: To confirm alpha-1-AT deficiency status in duodenal ulcer using a combination of PCR and restricted enzyme digestion. METHODS: Fifty patients with endoscopically proven duodenal ulcer and hundred controls with no signs of the disease were included. Alpha-1-AT phenotypes were confirmed by polymerase chain reaction followed by restriction enzyme digestion. RESULTS: Alpha-1-AT concentration in duodenal...
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