Article
Methylenetetrahydrofolate reductase polymorphism C677T is not associated to the risk of cervical dysplasia.
Cancer letters - 10 Mar 2003
Lambropoulos A F, Agorastos T, Foka Z J, Chrisafi S, Constantinidis T C, Bontis J, Kotsis A
Abstract excerpt
The aim of the study was to explore a possible association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and cervical neoplasia. A total of 229 women were subjected to cytologic and colposcopic evaluation. Ninety-one of them were found to be normal, and served as the cont...
Topics
- Adult
- Case-Control Studies
- Cohort Studies
- DNA Methylation
- DNA Primers
- Female
- Folic Acid
- Genetic Predisposition to Disease
- Genotype
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- Microsatellite Repeats
- Middle Aged
- Neoplasm Invasiveness
- Odds Ratio
- Oxidoreductases Acting on CH-NH Group Donors
- Polymerase Chain Reaction
- Polymorphism, Genetic