Article
Recurrent B-cell neoplasms after Rituximab therapy: an immunophenotypic and genotypic study.
Leukemia & lymphoma - 1 Dec 2002
Chu Peiguo G, Chen Yuan-Yuan, Molina Arturo, Arber Daniel A, Weiss Lawrence M
Abstract excerpt
Rituximab has been widely used to treat relapsing or advanced stage B-cell neoplasms with an efficacy of about 50%. However, approximately 40-50% of Rituximab treated patients will recur. It is not clear whether these recurrent diseases have the same immunophenotype as that of the original tumors. At the City of Hope, we treated 91 cases of CD20-positive B-cell neoplasms with Rituximab in combination with...
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