Article
Differences in chicken major histocompatibility complex (MHC) class Ialpha gene expression between Marek's disease-resistant and -susceptible MHC haplotypes.
Scandinavian journal of immunology - 1 Feb 2003
Dalgaard T S, Højsgaard S, Skjødt K, Juul-Madsen H R
Abstract excerpt
The expression of chicken major histocompatibility complex (MHC) class Ialpha genes was investigated in spleen cells from a panel of chickens with well-defined MHC haplotypes, and two class Ialpha transcripts of 1.9 and 1.5 kb were detected in various amounts. In BW1, B130 and B21, the two transcripts were almost equally expressed. In B2, B6, B12 and B19, the ratio between the two transcripts was 4 : 1, with the...
Topics
- Animals
- Blotting, Northern
- Chickens
- Gene Expression Regulation
- Genes, MHC Class I
- Genetic Predisposition to Disease
- Haplotypes
- Marek Disease
- RNA, Messenger
- Specific Pathogen-Free Organisms
- Spleen