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Article

Major histocompatibility complex and background genes in chickens influence susceptibility to high pathogenicity avian influenza virus.

Avian diseases - 1 Mar 2010

Hunt Henry D, Jadhao Samadhan, Swayne David E

Abstract excerpt

The chicken's major histocompatibility complex (MHC) haplotype has profound influence on the resistance or susceptibility to certain pathogens. For example, the B21 MHC haplotype confers resistance to Marek's disease (MD). However, non-MHC genes are also important in disease resistance. For example, lines 6 and 7 both express the B2 MHC haplotype, but differ in non-MHC genes. Line 6, but not line 7, is highly...

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PMID: 20521696
DOI: 10.1637/8888-042409-ResNote.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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