Article
Nontransmissible virus-like particle formation by F-deficient sendai virus is temperature sensitive and reduced by mutations in M and HN proteins.
Journal of virology - 1 Mar 2003
Inoue Makoto, Tokusumi Yumiko, Ban Hiroshi, Kanaya Takumi, Tokusumi Tsuyoshi, Nagai Yoshiyuki, Iida Akihiro, Hasegawa Mamoru
Abstract excerpt
The formation of nontransmissible virus-like particles (NTVLP) by cells infected with F-deficient Sendai virus (SeV/deltaF) was found to be temperature sensitive. Analysis by hemagglutination assays and Western blotting demonstrated that the formation of NTVLP at 38 degrees C was about 1/100 of that at 32 degrees C, whereas this temperature-sensitive difference was only moderate in the case of F-possessing...
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