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Article

GUN4, a regulator of chlorophyll synthesis and intracellular signaling.

Science (New York, N.Y.) - 7 Feb 2003

Larkin Robert M, Alonso Jose M, Ecker Joseph R, Chory Joanne

Abstract excerpt

Nuclear genes control plastid differentiation in response to developmental signals, environmental signals, and retrograde signals from plastids themselves. In return, plastids emit signals that are essential for proper expression of many nuclear photosynthetic genes. Accumulation of magnesium-protoporphyrin IX (Mg-Proto), an intermediate in chlorophyll biosynthesis, is a plastid signal that represses nuclear...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12574634
DOI: 10.1126/science.1079978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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GUN4, a regulator of chlorophyll synthesis and intracellular signaling.PMID 12574634Read ↗

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Influence of plastids on light signalling and development.Semantic proximity Read ↗

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In vivo visualization of Mg-protoporphyrin IX, a coordinator of photosynthetic gene expression in the nucleus and the chloroplast.Semantic proximity Read ↗

GUN1 Controls Accumulation of the Plastid Ribosomal Protein S1 at the Protein Level and Interacts with Proteins Involved in Plastid Protein Homeostasis.Semantic proximity Read ↗

Retrograde signaling and photoprotection in a gun4 mutant of Chlamydomonas reinhardtii.Semantic proximity Read ↗

The steady-state level of Mg-protoporphyrin IX is not a determinant of plastid-to-nucleus signaling in Arabidopsis.Semantic proximity Read ↗

Rice Chlorina-1 and Chlorina-9 encode ChlD and ChlI subunits of Mg-chelatase, a key enzyme for chlorophyll synthesis and chloroplast development.Semantic proximity Read ↗

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