Article
Homocysteine levels and C677T polymorphism of methylenetetrahydrofolate reductase in women with polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism - 1 Feb 2003
Orio Francesco, Palomba Stefano, Di Biase Sebastiano, Colao Annamaria, Tauchmanova Libuse, Savastano Silvia, Labella Donato, Russo Tiziana, Zullo Fulvio, Lombardi Gaetano
Abstract excerpt
The aim of this study was to investigate the homocysteine (Hcy) levels and the C677T polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR), a crucial factor of the Hcy metabolism in young women with polycystic ovary syndrome (PCOS). Seventy young women with PCOS and another 70 healthy women with low folate intake were enrolled. Cases and controls were matched for age, body mass index, and allele...
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