Schizophrenia and bipolar disorder: similarities in pathogenic mechanisms but differences in neurodevelopment.

Abstract excerpt

Over the past 100 years, the Kraepelinian classification of psychoses has dominated our approach to schizophrenia and bipolar disorder. However, controversy as to the nature of the illnesses--whether they can be viewed as completely distinct, essentially the same, or occupying different points along a psychosis spectrum--has intensified in recent years. This paper reviews the evidence for these differing...

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