Article
From lineage to wiring specificity. POU domain transcription factors control precise connections of Drosophila olfactory projection neurons.
Cell - 24 Jan 2003
Komiyama Takaki, Johnson Wayne A, Luo Liqun, Jefferis Gregory S X E
Abstract excerpt
Axonal selection of synaptic partners is generally believed to determine wiring specificity in the nervous system. However, we have recently found evidence for specific dendritic targeting in the olfactory system of Drosophila: second order olfactory neurons (Projection Neurons) from the anterodorsal (adPN) and lateral (lPN) lineages send their dendrites to stereotypical, intercalating but non-overlapping...
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