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Article

Acrokeratosis verruciformis of Hopf is caused by mutation in ATP2A2: evidence that it is allelic to Darier's disease.

The Journal of investigative dermatology - 1 Feb 2003

Dhitavat Jittima, Macfarlane Sarah, Dode Leonard, Leslie Natalie, Sakuntabhai Anavaj, MacSween Ruth, Saihan Eric, Hovnanian Alain

Abstract excerpt

Acrokeratosis verruciformis of Hopf is a localized disorder of keratinization affecting the distal extremities. Onset is early in life and the disease is inherited in an autosomal dominant fashion. Although histology of acrokeratosis verruciformis lesions shows no evidence of dyskeratosis, a possible relationship with Darier's disease has long been postulated on the basis of clinical similarity. ATP2A2 encoding...

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Identifiers

PMID: 12542527
DOI: 10.1046/j.1523-1747.2003.t01-1-12045.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Acrokeratosis verruciformis of Hopf is caused by mutation in ATP2A2: evidence that it is allelic to Darier's disease.PMID 12542527Read ↗

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