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Article

Levels of polymorphism on the sex-limited chromosome: a clue to Y from W?

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2003

Ellegren Hans

Abstract excerpt

Nucleotide diversity of the human Y chromosome is much lower than that in the rest of the genome. A new hypothesis postulates that this invariance may result from mutations in maternally inherited mitochondrial DNA (mtDNA), leading to impaired reproduction among males and lowered male effective population size. If correct, we should expect to see low levels of polymorphism in the male-specific Y chromosome of...

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PMID: 12539242
DOI: 10.1002/bies.10228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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