Article
Genetic variation in apolipoprotein D affects the risk of Alzheimer disease in African-Americans.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2003
Desai Purnima P, Hendrie Hugh C, Evans Rebecca M, Murrell Jill R, DeKosky Steven T, Kamboh M Ilyas
Abstract excerpt
Apolipoprotein D (APOD, gene; apoD, protein) is involved in neuroregenerative and neurodegenerative processes, and is upregulated in late-onset Alzheimer disease (AD) patients compared to nondemented controls. No genetic association studies have yet been carried out to investigate the role of APOD in AD. We have reported recently several sequence variants in the APOD gene, which are present exclusively among...
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