Article
Atomic force microscopy investigation of fibroblasts infected with wild-type and mutant murine leukemia virus (MuLV).
Biophysical journal - 1 Dec 2002
Kuznetsov Yurii G, Datta Shoibal, Kothari Natantara H, Greenwood Aaron, Fan Hung, McPherson Alexander
Abstract excerpt
NIH 3T3 cells were infected in culture with the oncogenic retrovirus, mouse leukemia virus (MuLV), and studied using atomic force microscopy (AFM). Cells fixed with glutaraldehyde alone, and those postfixed with osmium tetroxide, were imaged under ethanol according to procedures that largely preserved their structures. With glutaraldehyde fixation alone, the lipid bilayer was removed and maturing virions were...
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