Article
Rostral ventromedial medulla neurons that project to the spinal cord express multiple opioid receptor phenotypes.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Dec 2002
Marinelli Silvia, Vaughan Christopher W, Schnell Stephen A, Wessendorf Martin W, Christie MacDonald J
Abstract excerpt
The rostral ventromedial medulla (RVM) forms part of a descending pathway that modulates nociceptive neurotransmission at the level of the spinal cord dorsal horn. However, the involvement of descending RVM systems in opioid analgesia are a matter of some debate. In the present study, patch-clamp recordings of RVM neurons were made from rats that had received retrograde tracer injections into the spinal cord....
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