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Article

Defined human cellular systems in the study of glioma development.

Frontiers in bioscience : a journal and virtual library - 1 Jan 2003

Pieper Russell O

Abstract excerpt

The creation and characterization of permanent cell lines derived from primary human gliomas in the 1960s gave scientists access to unlimited, renewable material in which to study the development of brain tumors. These cells, however, were already tumorigenic and selected for growth in culture, limiting the amount of information that could be gathered about the events that led to the formation of their tumors of...

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PMID: 12456369
DOI: 10.2741/983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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