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Article

Distribution and possible function of an adrenomedullin-like peptide in the developing chick limb bud.

The International journal of developmental biology - 1 Jan 2002

Seghatoleslami M Reza, Martínez Alfredo, Cuttitta Frank, Kosher Robert A

Abstract excerpt

Adrenomedullin (AM) is a multifunctional peptide that exhibits discrete domains of expression during mouse embryogenesis consistent with a role in regulating growth and differentiation during morphogenesis. Here we report that AM immunoreactivity is present at high levels throughout the apical ectodermal ridge (AER) of the chick limb bud as the AER is directing the outgrowth and patterning of underlying limb...

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PMID: 12455634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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