Article
Analysis of variation in tandem repeats in the intron of the major surface glycoprotein expression site of the human form of Pneumocystis carinii.
The Journal of infectious diseases - 1 Dec 2002
Ma Liang, Kutty Geetha, Jia Qiuyao, Imamichi Hiromi, Huang Laurence, Atzori Chiara, Beckers Pieter, Groner Gena, Beard Charles B, Kovacs Joseph A
Abstract excerpt
Variation in the tandem repeats in the expression site of the human-derived Pneumocystis carinii major surface glycoprotein gene was characterized by denaturing gel electrophoresis. The number of repeats in 147 isolates ranged from 2 to 6, with 2, 3, and 4 repeats being the most common. Sequence analysis identified 3 types of repeat units that differed by 1 nucleotide, which suggests a hierarchy of evolution of...
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