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Article

Constitutive and Cytokine-Induced Expression of the ETS Transcription Factor ESE-3 in the Lung

1 Dec 2002

Abstract excerpt

Family studies of asthma suggest that the genes ESE-2 and ESE-3 contain polymorphisms that contribute to disease susceptibility. Each gene codes for an ETS transcription factor that is characterized by epithelium-restricted constitutive expression and may function as a context-dependent activator or repressor of transcription; however, nothing is known about the role of these genes in lung homeostasis or the...

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PMID: 12444029
DOI: 10.1165/rcmb.2002-0011oc

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