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Article

T <b>H</b> 2-Mediated Pulmonary Inflammation Leads to the Differential Expression of Ribonuclease Genes by Alveolar Macrophages

1 Dec 2002

Abstract excerpt

The eosinophil-associated ribonuclease (Ear) family in the mouse consists of thirteen genes, eleven of which encode RNases that have physical/functional properties similar to the human Ears, eosinophil-derived neurotoxin and eosinophil cationic protein. The expression of Ear genes in the mouse is confined to sites of known eosinophilopoiesis, with the exception of the lung. Two Ear genes, Ear1 and Ear2, are...

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PMID: 12444027
DOI: 10.1165/rcmb.4882

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