Article
Analysis of Ebh, a 1.1-megadalton cell wall-associated fibronectin-binding protein of Staphylococcus aureus.
Infection and immunity - 1 Dec 2002
Clarke Simon R, Harris Llinos G, Richards R Geoff, Foster Simon J
Abstract excerpt
In order for Staphylococcus aureus to adhere to host extracellular matrix (ECM) substrates, it elicits a wide range of surface proteins. We have characterized a novel approximately 1.1-MDa protein in S. aureus, termed Ebh (for ECM-binding protein homologue), which has homology to other ECM-binding proteins. Ebh consists of several domains, including a large central region with 44 imperfect repeats of 126 amino...
Topics
- Abscess
- Adhesins, Bacterial
- Animals
- Bacterial Proteins
- Carrier Proteins
- Cell Wall
- Disease Models, Animal
- Fibronectins
- Gene Expression Regulation, Bacterial
- Humans
- Mice