Article
Identification and characterization of a novel 38.5-kilodalton cell surface protein of Staphylococcus aureus with extended-spectrum binding activity for extracellular matrix and plasma proteins.
Journal of bacteriology - 1 Dec 2001
Hussain M, Becker K, von Eiff C, Schrenzel J, Peters G, Herrmann M
Abstract excerpt
The ability to attach to host ligands is a well-established pathogenic factor in invasive Staphylococcus aureus disease. In addition to the family of adhesive proteins bound to the cell wall via the sortase A (srtA) mechanism, secreted proteins such as the fibrinogen-binding protein Efb, the extracellular adhesion protein Eap, or coagulase have been found to interact with various extracellular host molecules....
Topics
- Adhesins, Bacterial
- Amino Acid Sequence
- Bacterial Adhesion
- Bacterial Proteins
- Blood Proteins
- Extracellular Matrix Proteins
- Molecular Sequence Data
- Molecular Weight
- Phenotype
- Protein Binding
- Staphylococcus aureus