Low or absent unconjugated estriol in pregnancy: an indicator for steroid sulfatase deficiency detectable by fluorescence <i>in situ</i> hybridization and biochemical analysis

Abstract excerpt

It has been previously reported that a low or absent maternal serum unconjugated estriol (uE3) level is associated with placental steroid sulfatase (STS) deficiency. Here we report a correlation between patients who present with a very low or absent maternal serum uE3 and a deletion of the STS gene as assessed by fluorescence in situ hybridization (FISH). We studied nine prenatal cases that presented to the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gestational Trophoblastic Disease Studies
• Share to Neonatal Respiratory Health Research
• Share to Prenatal Screening and Diagnostics