Article
Sex-typed toy play behavior correlates with the degree of prenatal androgen exposure assessed by CYP21 genotype in girls with congenital adrenal hyperplasia.
The Journal of clinical endocrinology and metabolism - 1 Nov 2002
Nordenström Anna, Servin Anna, Bohlin Gunilla, Larsson Agne, Wedell Anna
Abstract excerpt
Previous studies have shown that girls with congenital adrenal hyperplasia (CAH), a syndrome resulting in overproduction of adrenal androgens from early fetal life, are behaviorally masculinized. We studied play with toys in a structured play situation and correlated the results with disease severity, assessed by CYP21 genotyping, and age at diagnosis. Girls with CAH played more with masculine toys than controls...
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