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Article

Apolipoprotein E and apolipoprotein B genotypes and risk for spina bifida.

Teratology - 1 Nov 2002

Volcik Kelly A, Zhu Huiping, Shaw Gary M, Lammer Edward J, Finnell Richard H

Abstract excerpt

BACKGROUND: Altered cholesterol metabolism and defects in cholesterol biosynthesis may influence abnormal central nervous system (CNS) development. During early stages of embryonic development, high levels of cholesterol are needed by rapidly proliferating cells that utilize cholesterol as a key cell membrane component. Alterations in cholesterol levels are influenced by variations in the apolipoprotein E (apoE)...

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PMID: 12397634
DOI: 10.1002/tera.10097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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