Article
[Analysis of the proteomic changes of the serum of the Smad3 targeted deficient mice].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Jul 2002
Hao Zhen-Ming, Yang Xiao, Ying Wan-Tao, Wang Jie, Qian Xiao-Hong, Huang Cui-Fen
Abstract excerpt
We have studied the proteomic changes of the serum of the Smad3 targeted deficient mice using 2-DE and PMF approaches. 7 proteins expressed at different level in wild type mice and the Smad3 deficient mice were identified. These results would benefit the research on diagnosis and therapy of osteoarthritis and provided clues to studying the important function of Smad3 mediated TGF-beta signals during the skeletal...
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