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Article

Nucleotide variations in the lxd region of Drosophila melanogaster: characterization of a candidate modifier of lifespan.

Gene - 4 Sept 2002

Tahoe N M A, Dean A M, Curtsinger J W

Abstract excerpt

We have investigated the structure and function of several proteins that might influence adult lifespans in Drosophila melanogaster. The present report focuses on the gene lxd ('low xanthine dehydrogenase'), which lies in a region of chromosome III identified by QTL-mapping as potentially important for lifespan. DNA sequence of a 3780 bp genomic fragment containing the lxd locus reveals differences between...

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PMID: 12384303
DOI: 10.1016/s0378-1119(02)00916-2

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